Abstract
Background and Objectives : Neurological manifestations have been reported in a significant proportion of coronavirus disease 2019 (COVID-19) patients. We aimed to evaluate the prevalence and severity of peripheral nervous system (PNS) involvement in a large group of convalescent COVID-19 patients undergoing in-hospital multidisciplinary rehabilitation. Materials and Methods : Convalescent COVID-19 patients admitted to a Pulmonary Rehabilitation Unit were consecutively screened for inclusion within 48 h of discharge from an acute care setting. All included patients underwent electrophysiological examinations. Results : Among 102 enrolled patients (mean age 62.0 years, 82.4% males), PNS electrophysiological alterations were detected in 42.2%. Mononeuropathies exclusively involving the peroneal nerve were observed in 8.8% ( n = 9), while multiple mononeuropathies were similarly reported in nine patients (8.8%). A symmetric sensorimotor polyneuropathy was documented in 24.5% of participants ( n = 25). A significant difference was found for exercise capacity and pulmonary function in post hoc comparisons between the three study groups. Conclusions : The risk of neuropathy in the convalescent phase of COVID-19 is relevant. This should be considered when planning multidisciplinary rehabilitation strategies.
Keywords: COVID-19; SARS-CoV-2; chronic disease; disability; exercise; neuropathy; occupational medicine; outcome; rehabilitation.
【저자키워드】 COVID-19, SARS-CoV-2, exercise, occupational medicine, outcome, chronic disease, disability, rehabilitation., Neuropathy, 【초록키워드】 coronavirus disease, exercise, Coronavirus disease 2019, severity, Exercise capacity, risk, rehabilitation, occupational medicine, pulmonary, discharge, chronic disease, Prevalence, Pulmonary function, comparison, Patient, nervous system, neurological manifestations, age, disability, pulmonary rehabilitation, Care, patients, convalescent COVID-19 patients, Peripheral nervous system, COVID-19 patient, Neuropathy, manifestation, In-hospital, Polyneuropathy, significant difference, convalescent phase, alteration, participant, study groups, material, unit, objective, males, Peroneal nerve, Result, enrolled, evaluate, proportion, reported, nine, screened, convalescent COVID-19 patient, for inclusion, Mononeuropathy, 【제목키워드】 peripheral, Sery,