Abstract
Giant cell myocarditis (GCM) is a rare condition. Its association with SARS-CoV-2 has not been described before. The 46-year-old female patient was admitted to the clinic on September 2020. She had 7 year adrenal insufficiency history and infarct-like debut of myocardial disease in November 2019. After COVID-19 in April 2020, cardiac disease progressed. The examination showed low QRS voltage, QS complexes in V 1 -V 5 leads, atrial standstill, left ventricular systolic and restrictive dysfunction, elevated anti-heart antibodies, and subepicardial late gadolinium enhancement by magnetic resonance imaging. Endomyocardial biopsy and pacemaker implantation were performed, but the patient died suddenly due to ventricular tachycardia or ventricular fibrillation (the resuscitation was ineffective). The autopsy revealed GCM, SARS-CoV-2, and Parvovirus B19 were detected in the myocardium. The role of SARS-CoV-2 in the pathogenesis of autoimmune myocarditis is discussed.
Keywords: Atrial standstill; Endomyocardial biopsy; Giant cell myoendocarditis; SARS-CoV-2; Sudden cardiac death.
【저자키워드】 SARS-CoV-2, Endomyocardial biopsy, Atrial standstill, Giant cell myoendocarditis, sudden cardiac death, 【초록키워드】 COVID-19, antibodies, Pathogenesis, magnetic resonance imaging, Autopsy, Endomyocardial biopsy, Resuscitation, myocarditis, female, Patient, Adrenal insufficiency, Autoimmune, cardiac disease, disease, association, Atrial standstill, giant cell myocarditis, Infarct, sudden cardiac death, ventricular tachycardia, ventricular fibrillation, giant cell, gadolinium, dysfunction, Tachycardia, Myocardium, cardiac death, examination, clinic, Parvovirus, Myocardial, myoendocarditis, described, performed, died, the patient, elevated, complexes, progressed, ventricular, 【제목키워드】 death, Atrial standstill, Giant, Cell, Progressive,