Abstract
Background and objective: The objective was to describe the clinical characteristics and prognosis of patients with nosocomial SARS-CoV-2 infection.
Methods: An observational and prospective study was performed in a referral hospital. We included all adult patients diagnosed with nosocomial SARS-CoV-2 infection in October 2020. Nosocomial infection was defined as a negative PCR for SARS-CoV-2 on admission and a positive PCR after 7 days of hospitalization.
Results: We included 66 cases of nosocomial SARS-CoV-2 infection: 39 (59%) men, median age at diagnosis was 74.5 years (IQR 56.8-83.1) and median Charlson comorbidity index was 3 points (IQR 1-5). Twenty-seven (41%) developed pneumonia and 13 (20%) died during admission. Mortality at 28 days was 33% (22 patients). Mortality at 28 days in the 242 patients with community-acquired SARS-CoV-2 infection who were hospitalized during the same period was 10%.
Conclusions: Preventive measures and early detection of nosocomial outbreaks of COVID-19 should be prioritized to minimize the negative impact of this infection.
Keywords: COVID-19; Control de infección; Coronavirus; Infection control; Nosocomial; Prevención; Prevention; SARS-CoV-2.
【저자키워드】 COVID-19, infection control, coronavirus, nosocomial, prevention, SARS-CoV-2., Prevención, Control de infección, 【초록키워드】 SARS-CoV-2, infection control, Hospitalized, Prognosis, Hospitalization, Clinical characteristics, Pneumonia, SARS-COV-2 infection, hospital, Prospective Study, nosocomial, Infection, Diagnosis, Comorbidity, Early detection, Patient, Nosocomial infection, Control, nosocomial outbreak, preventive measures, Nosocomial outbreaks, Admission, patients, preventive measure, during admission, median age, Negative PCR, positive PCR, men, defined, died, diagnosed, was performed, median, prognosis of patient, IQR, 【제목키워드】 hospital, Prospective,