Abstract
Clinical testing of children in schools is challenging, with economic implications limiting its frequent use as a monitoring tool of the risks assumed by children and staff during the COVID-19 pandemic. Here, a wastewater-based epidemiology approach has been used to monitor 16 schools (10 primary, 5 secondary and 1 post-16 and further education) in England. A total of 296 samples over 9 weeks have been analysed for N1 and E genes using qPCR methods. Of the samples returned, 47.3% were positive for one or both genes with a detection frequency in line with the respective local community. WBE offers a low cost, non-invasive approach for supplementing clinical testing and can provide longitudinal insights that are impractical with traditional clinical testing.
【초록키워드】 Epidemiology, children, COVID-19 pandemic, risk, Local, Schools, qPCR, clinical, Community, School, England, Frequency, Non-invasive, E gene, clinical testing, positive, offer, MONITOR, implication, approach, analysed, returned, assumed, 【제목키워드】 SARS-CoV-2, monitoring, approach, Occurrence,