Abstract
Background: Increased coronavirus disease 2019 (COVID-19) incidence and mortality in hospitalised patients with psychiatric and neurologic disorders have been reported.
Methods: The clinical records of 198 patients with psychiatric and neurological disorders hospitalised in the Dr Rafael Serrano Psychiatric Hospital in Puebla during the peak of the first wave of the COVID-19 pandemic in Mexico were analysed for psychiatric or neurologic diagnosis, gender, age, medical diagnosis, and COVID-19 prevalence. For patients with COVID-19, the effects of gender, and medical diagnosis were explored.
Results: There was an increased COVID-19 prevalence in the studied population (43.94%), compared with the national Mexican (~0.21% to 0.63%) and worldwide average in the general population (~0.13% to 4.28%). However, the mortality rate (5.75%) was lower than that reported in Mexico (11.28%-13.55%), which was higher than the worldwide average (2.95%-4.98%). We detected increased COVID-19 prevalence in patients with comorbidities (odds ratios [OR] 0.4; 95% CI: 0.2-1, P = .0447). Moreover, patients with schizophrenia spectrum disorders have a decreased predisposition to COVID-19 (OR 0.4, 95% CI: 0.2-0.8; P = .0250), as opposed to patients with intellectual disability that are predisposed to COVID-19 (OR 2.2, 95% CI: 0.2-0.8; P = .0434), in comparison with the rest of the hospital population.
Conclusion: The prevalence of COVID-19 in hospitalised patients with psychiatric disorders is increased compared with that of the general population; however, a lower mortality rate was detected. Also, an increased risk of COVID-19 was detected in patients with comorbidities. Interestingly, the observed variation in COVID-19 prevalence in patients with schizophrenia and intellectual disability was not associated with age or other specific medical diagnoses.
【초록키워드】 COVID-19, coronavirus disease, Coronavirus disease 2019, Mortality, COVID-19 pandemic, hospital, Variation, Comorbidities, Diagnosis, Gender, Prevalence, intellectual disability, Patient, age, Hospitalised patients, Psychiatric disorders, Schizophrenia, General population, mortality rate, incidence, medical diagnosis, Neurological disorders, First wave, Neurological disorder, Psychiatric Hospital, psychiatric disorder, Psychiatric, 95% CI, increased risk, diagnoses, Odds ratios, average, lower mortality, disorder, National, predisposition, neurologic disorders, Effect, neurologic, hospitalised, reported, analysed, hospitalised patient, Increased, neurologic disorder, patients with comorbidities, patients with comorbidity, patients with COVID-19, prevalence of COVID-19, 【제목키워드】 COVID-19, Prevalence, Retrospective analysis, neurological, hospitalised patient,