In 2012-2013, we examined 1729 laboratory-confirmed A(H1N1)pdm09 influenza cases matched 1:1 with healthy controls and estimated influenza vaccine effectiveness (VE) for trivalent inactivated influenza vaccine (IIV3) to be 67% (95% confidence interval=58-74%) for ages 8 months to 6 years old. Among children aged 8-35 months old, VE for fully vaccinated children (73%, 60-81%) was significantly higher than VE for partially vaccinated children (55%, 33-70%). Significant cross-season protection from prior IIV3 was noted, including VE of 31% (8-48%) from IIV3 received in 2010-2011 against influenza illness in 2012–2013 without subsequent boosting doses.
All Keywords
【저자키워드】 children, vaccine effectiveness, influenza vaccines, A(H1N1)pdm09 influenza, prior vaccination,
【저자키워드】 children, vaccine effectiveness, influenza vaccines, A(H1N1)pdm09 influenza, prior vaccination,