Depression and anxiety in cancer patients before and during the SARS-CoV-2 pandemic: association with treatment delays

SARS-CoV-2 대유행 전과 기간 동안 암 환자의 우울증과 불안: 치료 지연과의 연관성

Published on
Journal: Quality of life research : an international journa
[저자] Ozgen Ahmet Yildirim, Kerem Poyraz, Erkan Erdur
[Category] SARS, 치료기술,
PMC URL    [DOI] 10.1007/s11136-021-02795-4    
[Article Type] Article
[Source] PMC

Abstract
Purpose: Pandemics can be associated with anxiety and depression in cancer patients who are undergoing treatment. In the present study, we aimed to perform a comparative evaluation of the conditions of cancer patients before and during the severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) pandemic using the Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) to detect the impact of the pandemic on treatment delays that are associated with anxiety and depression in cancer patients. In addition, the effect of public transport use on treatment delays was examined.
Methods: BDI and BAI were administered to 595 breast, ovarian, colon and gastric cancer patients before and during the pandemic. The questionnaires were administered by the physician blindly, who was unaware of the delay of the patients. The number of days by which the patients delayed their treatment due to the fear of contamination were recorded retrospectively. Correlation analyses were performed between the obtained scores and treatment delays.
Results: The depression and anxiety levels in cancer patients were found to increase during the pandemic (p = 0.000), and this increase was positively correlated with the disruption of their treatment (p = 0.000, r = 0.81). Depression and anxiety levels and treatment delays were higher in elderly patients (p = 0.021). Depression and anxiety were more pronounced in female patients (p = 0.000). Moreover, treatment delays were more common in patients who had to use public transportation (p = 0.038).
Conclusion: SARS-CoV-2 pandemic may increase anxiety and depression in cancer patients. This can cause patients to experience treatment delays due to concerns about becoming infected. At this point, if necessary, assistance should be obtained from psychiatric and public health experts.
Keywords: Anxiety; Cancer patients; Depression; SARS-CoV-2.

All Keywords
【저자키워드】 SARS-CoV-2, Anxiety, Depression, Cancer patients, 【초록키워드】 Treatment, public health, SARS-CoV-2, coronavirus, pandemic, acute respiratory distress syndrome, SARS-CoV-2 pandemic, elderly patients, Contamination, Patient, Cancer patients, Pandemics, public transport, questionnaire, patients, acute respiratory distress, Elderly patient, Disruption, cancer patient, respiratory distress, Transport, Questionnaires, Psychiatric, Colon, Correlation analysis, Beck, assistance, syndrome, Female patients, physician, correlation analyses, ovarian, Administered, inventory, fear of contamination, performed, detect, examined, the patient, addition, condition, female patient, were recorded, BAI, positively correlated, 【제목키워드】 Treatment, association, cancer patient, the SARS-CoV-2,
{{{ 추상적인 }}} {{ 목적: }} 전염병은 치료를 받고 있는 암 환자의 불안과 우울증과 관련될 수 있습니다. 본 연구에서는 Beck Depression Inventory(BDI)와 Beck Anxiety Inventory( BAI)는 암 환자의 불안과 우울증과 관련된 치료 지연에 대한 전염병의 영향을 감지합니다. 또한 대중교통 이용이 치료지연에 미치는 영향을 조사하였다. {{ 방법: }} BDI와 BAI는 대유행 전후에 595명의 유방암, 난소암, 결장암 및 위암 환자에게 투여되었습니다. 설문지는 환자의 지연을 인지하지 못한 의사가 맹목적으로 실시하였다. 환자가 오염에 대한 두려움으로 치료를 미루는 일수를 후향적으로 기록하였다. 획득한 점수와 치료 지연 사이의 상관 분석을 수행했습니다. {{ 결과: }} 대유행 기간 동안 암 환자의 우울증과 불안 수준이 증가한 것으로 나타났으며(p = 0.000), 이러한 증가는 치료 중단과 양의 상관관계가 있었습니다(p = 0.000, r = 0.81). 우울증과 불안 수준 및 치료 지연은 노인 환자에서 더 높았다(p=0.021). 우울증과 불안은 여성 환자에서 더 두드러졌습니다(p = 0.000). 또한 대중교통을 이용해야 하는 환자에서 치료 지연이 더 흔했다(p=0.038). {{ 결론: }} SARS-CoV-2 대유행은 암 환자의 불안과 우울증을 증가시킬 수 있습니다. 이로 인해 환자는 감염에 대한 우려로 인해 치료가 지연될 수 있습니다. 이때 필요한 경우 정신과 및 공중보건 전문가의 도움을 받아야 합니다. {{ 키워드: }} 불안; 암 환자; 우울증; 사스 코로나바이러스 2.