Abstract
A number of unexplained cases of pneumonia have been recorded since November 2019 in China. It is officially named the new corona virus (2019-nCov) by the World Health Organization on 12 January 2020. WHO officially named it COVID-19 on 11 February. COVID-19 is a highly transmitted and pathogenic viral infection that has been developed and spread across the world in Wuhan, China, caused by extreme acute respiratory syndrome corona-virus 2 (SARS-CoV-2). Genomic analysis showed that bats may also be a primary reservoir of SARS-CoV-2 phylogenetically associated with severe acute respiratory syndrome-like viruses (SARS). However, the rapid human to human transition has been generally reported. Intermediate source of origin and human transition is unknown. Clinically approved COVID-19 antiviral medication or vaccine is not available. In clinical trials, however, few broad-based COVID-19 antiviral medicinal drugs were tested, resulting in clinical recovery. This analysis summarizes the pathogenicity of COVID-19 and aims to raise awareness of COVID-19 among the population and to continually boost the detection, monitoring, diagnosis and care level. Over 50 COVID-19 scientific publications were included in this systematic analysis. We found that fever (87.0%), cough (65.9%) and malaise/tiredness (35%) were the most common symptoms of COvida-19. However, COVID-19 clinical signs and symptoms were not necessarily obvious. The transmission of COVID-19 in comparison to SARS was more specific. The rate of death of COVID-19 was 2,7% and the pathological characteristics of COVID-19 are very similar to ARDS. There are also discussions on the latest epidemiological changes, clinical manifestations, auxiliary examination and COVID-19 pathological characteristics.
Keywords: Antiviral medicinal drugs; COVID-19; Corona virus; Epidemiological characteristics; Pathological characteristics.
【저자키워드】 COVID-19, Corona virus, Epidemiological characteristics, Antiviral medicinal drugs, Pathological characteristics, 【초록키워드】 viruses, SARS-CoV-2, viral infection, Corona virus, ARDS, Vaccine, Antiviral, Pneumonia, 2019-nCoV, Diagnosis, clinical trials, Transmission, Symptom, drug, cough, virus, clinical manifestations, Spread, clinical recovery, China, Severe acute respiratory syndrome, Viral, Characteristics, Corona, Signs and symptoms, Fever, Wuhan, Awareness, death, bat, Genomic analysis, Clinical signs, WHO, epidemiological, respiratory, pathogenicity, Care, bats, boost, Analysis, Health Organization, World Health Organization, changes, acute respiratory syndrome, malaise, pathogenic, tiredness, intermediate, antiviral medication, over, Clinical sign, systematic analysis, Wuhan, China, raise, extreme, pathological, resulting, tested, caused, reported, transmitted, approved, recorded, phylogenetically, auxiliary, 【제목키워드】 COVID-19 pandemic, Transmission, Impact,