With the exponential growth of COVID-19 cases, the neurological complications reported during or after the infection became more common. There is limited knowledge regarding the pathophysiological mechanisms that are responsible for these complications. Recent data provides compelling evidence for the neurotropic nature of SARS-CoV-2, based on neurological manifestations reported during the current pandemic, as well as on previous experience with other coronaviruses. We present the case of a patient who developed headaches, motor deficit and dysphasia after respiratory COVID-19. Imaging tests showed heterogeneous central nervous system lesions (multiple subarachnoid hemorrhages and two ischemic strokes). Given the plethora of atypical neurological complications of COVID-19 described in the current literature, establishing a positive diagnosis and deciding on a treatment plan proved to be particularly challenging. We set to discuss some of the possible pathologies, hypothesized to be associated with COVID-19, that could lead to concomitant neurological lesions, similar to those noticed in our patient.
【저자키워드】 COVID-19, stroke, NEUROLOGY, cardiovascular medicine, subarachnoid hemorrhage, ACE2 – angiotensin converting enzyme II, BBB – blood-brain barrier, BMI – body mass index, BP – blood pressure, CNS – central nervous system, COVID-19 – coronavirus disease, CRP – C-reactive protein, CSF – cerebrospinal fluid, CT – Computer tomography, CTA – Computer tomography angiography, CVT – cerebral venous thrombosis, ECG – electrocardiogram, Holter ECG – Holter electrocardiogram, HR – heart rate, I.V. – intravenous, MRA – Magnetic resonance angiography, LMWH – low molecular weight heparin, MRC scale – Medical Research Council's scale, MRI – Magnetic resonance imaging, PACNS – primary angiitis of the central nervous system, PCA – posterior cerebral artery, PCoA – posterior communicating artery, PCR – polymerase chain reaction, RCVS – reversible cerebral vasoconstriction syndrome, RT-PCR – real-time polymerase chain reaction, RR – reference range, SAH – subarachnoid hemorrhage, SARS-CoV-2 – severe acute respiratory syndrome coronavirus 2, UL – upper limit, 【초록키워드】 Treatment, SARS-CoV-2, pandemic, knowledge, Infection, Diagnosis, imaging, Patient, complications, neurological manifestations, Central nervous system, Neurological complications, respiratory, Pathologies, Evidence, COVID-19 cases, Atypical, neurological, Neurological complication, lead, exponential growth, lesion, Headaches, growth, other coronaviruses, lesions, pathophysiological mechanism, heterogeneous, plethora, positive, pathophysiological mechanisms, neurological manifestation, recent, neurotropic, dysphasia, Imaging tests, responsible, described, reported, provide, with COVID-19, 【제목키워드】 diagnostic, Complication,