The data on seroprevalence of anti-SARS-CoV-2 antibodies in Kazakhstani population are non-existent, but are needed for planning of public health interventions targeted to COVID-19 containment. The aim of the study was to estimate the seropositivity of SARS-CoV-2 infection in the Kazakhstani population from 2020 to 2021. We relied on the data obtained from the results from “IN VITRO” laboratories of enzyme-linked immunosorbent assays for class G immunoglobulins (IgG) and class M (IgM) to SARS-CoV-2. The association of COVID-19 seropositivity was assessed in relation to age, gender, and region of residence. Additionally, we related the monitoring of longitudinal seropositivity with COVID-19 statistics obtained from Our World in Data. The total numbers of tests were 68,732 for SARS-CoV-2 IgM and 85,346 for IgG, of which 22% and 63% were positive, respectively. The highest rates of positive anti-SARS-CoV-2 IgM results were seen during July/August 2020. The rate of IgM seropositivity was the lowest on 25 October 2020 (2%). The lowest daily rate of anti-SARS-CoV-2 IgG was 17% (13 December 2020), while the peak of IgG seropositivity was seen on 6 June 2021 (84%). A longitudinal serological study should be envisaged to facilitate understanding of the dynamics of the epidemiological situation and to forecast future scenarios.
【저자키워드】 COVID-19, Surveillance, Seropositivity, Kazakhstan, 【초록키워드】 SARS-CoV-2, IgG, IgM, SARS-COV-2 infection, Seroprevalence, Gender, Laboratory, anti-SARS-CoV-2 antibodies, enzyme-linked immunosorbent assay, Immunoglobulin, anti-SARS-CoV-2 antibody, anti-SARS-CoV-2 IgG, enzyme-linked immunosorbent assays, Public health interventions, Seropositivity, age, serological, SARS-CoV-2 IgM, anti-SARS-CoV-2 IgM, association, Public health intervention, Planning, enzyme, epidemiological situation, residence, positive, lowest, highest, facilitate, with COVID-19, 【제목키워드】 SARS-CoV-2, Population, Seropositivity,