We describe the unique disease course and cure of SARS-CoV-2 infection in a patient with SCID and graft failure. In absence of a humoral immune response, viral clearance was only achieved after transfusion of convalescent plasma. This observation underscores the necessity of the humoral immune response for SARS-CoV-2 clearance.
All Keywords
【저자키워드】 convalescent plasma, SARS-CoV-2, Remdesivir, humoral immune response, severe combined immunodeficiency, 【초록키워드】 SARS-COV-2 infection, viral clearance, Patient, observation, disease course, SARS-CoV-2 clearance, absence, unique, 【제목키워드】 Graft, severe combined immunodeficiency, failure, over, Week,
【저자키워드】 convalescent plasma, SARS-CoV-2, Remdesivir, humoral immune response, severe combined immunodeficiency, 【초록키워드】 SARS-COV-2 infection, viral clearance, Patient, observation, disease course, SARS-CoV-2 clearance, absence, unique, 【제목키워드】 Graft, severe combined immunodeficiency, failure, over, Week,
우리는 SCID 및 이식 실패 환자의 SARS-CoV-2 감염의 독특한 질병 경과 및 치료에 대해 설명합니다. 체액성 면역 반응이 없는 경우, 바이러스 제거는 회복기 혈장을 수혈한 후에만 달성되었습니다. 이 관찰은 SARS-CoV-2 제거를 위한 체액성 면역 반응의 필요성을 강조합니다.