Introduction: The COVID-19 pandemic caused major changes in the lifestyle and in the access to health services worldwide. Progressive multiple sclerosis (pMS) patients are a vulnerable population at high risk of disability worsening.
Objective and methods: The objective of this study was to assess the health outcomes of COVID-19 lockdown in a cohort of 225 pMS patients.
Results: Worsening of neurological disability (19.7%) and fatigue (32.4%), depression (30.4%), and weight increase (28.3%) were observed in pMS patients during lockdown, along with discontinuation of regular physical exercise (47.1%) and of physical therapy (59.3%).
Conclusion: These results highlight the adverse impact, on pMS patients, of the public health measures implemented for the containment of the pandemic.
【저자키워드】 COVID-19, exercise, fatigue, lockdown, disability, Progressive multiple sclerosis.,