Abstract
Coronavirus disease 2019 (COVID-19) is a viral disease caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), a member of the Coronaviridae family. On March 11, 2020 the World Health Organization (WHO) has named the newly emerged rapidly-spreading epidemic as a pandemic. Besides the risk-reduction measures such as physical and social distancing and vaccination, a wide range of treatment modalities have been developed; aiming to fight the disease. The immune system is known as a double-edged sword in COVID-19 pathogenesis, with respect to its role in eliminating the pathogen and in inducing complications such as cytokine storm syndrome. Hence, immune-based therapeutic approaches have become an interesting field of COVID-19 research, including corticosteroids, intravenous immunoglobulins (IVIG), interferon therapy, and more COVID-19-specific approaches such as anti-SARS-CoV-2-monoclonal antibodies. Herein, we did a comprehensive review on immune-based therapeutic approaches for COVID-19. DATA AVAILABILITY STATEMENT: Not applicable.
Keywords: ARDS; COVID-19; Coronavirus; Corticosteroids; IVIG; Immune; Immunotherapy; Interferon; Monoclonal antibody; Pandemic; Pneumonia; SARS; SARS-CoV-2.
【저자키워드】 COVID-19, ARDS, coronavirus, Corticosteroids, pandemic, Pneumonia, Immunotherapy, monoclonal antibody, SARS, interferon, immune, IVIG, SARS-CoV-2., 【초록키워드】 Treatment, antibodies, SARS-CoV-2, Coronavirus disease 2019, Intravenous immunoglobulin, vaccination, therapy, social distancing, Cytokine storm syndrome, immune system, Epidemic, COVID-19 pathogenesis, pathogen, Complication, WHO, viral disease, Coronavirus-2, not applicable, World Health Organization, acute respiratory syndrome, measure, COVID-19 research, physical, caused, approach, the disease, the Coronaviridae, eliminating, therapeutic approach, 【제목키워드】 therapeutic approach,