Abstract
Objectives: To understand the sequelae of COVID-19.
Methods: We followed up 1174 patients with severe coronavirus disease 2019 (COVID-19)who were recovered and discharged for 6 months.
Results: There were 175 cases with clear IgG results 6 months after discharge, of which 82 (46.9%) were IgG (+) and 16 (9.1%) were IgG (dim+). Four hundred and forty-one participants (55.4%) had some kind of sequelae. The most common symptoms were fatigue (25.3%), sleep disorder (23.2%) and shortness of breath (20.4%). In those who had sequelae, 262 (59.4%) had more than one symptom. Critical cases were more likely to have cough (20.5% vs 11.6%, p = 0.023) and hypomnesis (15.1% vs 8.0%, p = 0.041) than severe cases. Furthermore, univariate and multivariate logistic regression analyses revealed that women are more likely to have multiple symptoms (p = 0.002), fatigue (p = 0.009) and sleep disorder (p = 0.008), whereas critical illness was found as independent risk factor for hypomnesis (p = 0.045).
Conclusion: Our study demonstrated the duration of antibody and sequelae of COVID-19 and compared the differences amongst different populations.
Keywords: COVID-19; SARS-CoV-2; follow-up; symptom.
【저자키워드】 COVID-19, SARS-CoV-2, Symptom, Follow-up, 【초록키워드】 IgG, fatigue, antibody, Symptom, cough, discharge, Patient, severe cases, women, Critical, Analysis, Shortness of breath, sleep disorder, severe coronavirus disease, multivariate logistic regression, participant, independent risk factor, populations, demonstrated, discharged, had more, 【제목키워드】 Symptom, risk factor, Patient,