Abstract
Background: The purpose of this study was to assess the occupational SARS-CoV-2 infection risk among health care workers (HCW) at University of Kentucky HealthCare (UKHC) by evaluating the prevalence of SARS-CoV-2 antibodies.
Methods: This is a prospective cohort study of HCW at UKHC. SARS-CoV-2 IgG antibody seropositivity was measured in a CLIA-certified laboratory utilizing the Abbott Architect SARS-CoV-2 IgG antibody assay. Demographics and work type were self-reported by study participants via an emailed survey.
Results: The overall antibody positivity rate of HCW was 1.55% (5/322; 95% confidence interval: 0.65%-3.71%) at cohort entry. There were no differences in antibody positivity between those that worked directly with SARS-CoV-2 infected patients and those that did not. The antibody rate of positivity of patients during the same time period was similar, 1.8% (9/499; 95% confidence interval 0.94%-3.45%).
Conclusions: Antibody positivity was low and similar between HCW and patients tested during a similar time period. HCW positivity rates did not appear to be impacted by caring for known SARS-CoV-2 infected patients suggesting that appropriate use of personal protective equipment is effective in protecting individuals from transmission.
Keywords: COVID-19; Health systems; Personal protective equipment.
【저자키워드】 COVID-19, Personal protective equipment, health systems, 【초록키워드】 Personal protective equipment, antibody, equipment, SARS-COV-2 infection, risk, Transmission, prospective cohort study, Laboratory, Prevalence, Cohort, SARS-CoV-2 antibodies, SARS-CoV-2 IgG antibody, Patient, Health care worker, Protective, Abbott, HCW, 95% confidence interval, individual, no difference, Architect, effective, was measured, tested, study participant, impacted, SARS-CoV-2 infected patient, University of Kentucky, 【제목키워드】 SARS-CoV-2 IgG antibody, Health care worker, infection risk, Care,