Abstract
Little is known about the cellular immune response to SARS-CoV-2 vaccination in patients after HSCT and B-NHL with iatrogenic B-cell aplasia. In nonseroconverted HSCT patients, induction of specific T-cell responses was assessed. The majority of allogeneic HSCT patients not showing humoral responses to vaccination also fail to mount antigen-specific T-cell responses.
Keywords: HSCT; SARS-CoV-2; SARS-CoV-2-specific T cells; vaccination.
All Keywords
【저자키워드】 SARS-CoV-2, vaccination, SARS-CoV-2-specific T cells, HSCT, 【초록키워드】 vaccination, Cellular immune response, Humoral response, Patient, T-cell responses, SARS-CoV-2 vaccination, B-cell, Specific T-cell response, allogeneic HSCT, majority, HSCT patients, iatrogenic, 【제목키워드】 COVID-19 vaccination, recipient, seroconvert, allogeneic HSCT, less, SARS-CoV-2-specific T cell,
【저자키워드】 SARS-CoV-2, vaccination, SARS-CoV-2-specific T cells, HSCT, 【초록키워드】 vaccination, Cellular immune response, Humoral response, Patient, T-cell responses, SARS-CoV-2 vaccination, B-cell, Specific T-cell response, allogeneic HSCT, majority, HSCT patients, iatrogenic, 【제목키워드】 COVID-19 vaccination, recipient, seroconvert, allogeneic HSCT, less, SARS-CoV-2-specific T cell,
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의인성 B 세포 무형성증이 있는 HSCT 및 B-NHL 후 환자에서 SARS-CoV-2 예방 접종에 대한 세포 면역 반응에 대해서는 알려진 바가 거의 없습니다. 혈청전환되지 않은 HSCT 환자에서 특정 T 세포 반응의 유도가 평가되었습니다. 백신 접종에 체액 반응을 나타내지 않는 동종 HSCT 환자의 대부분은 또한 항원 특이적 T 세포 반응을 나타내지 못합니다.
{{ 키워드: }} HSCT; 사스 코로나바이러스 2; SARS-CoV-2-특이적 T 세포; 백신 접종.