Abstract
While there are increasing reports of acute kidney injury among hospitalized adults with COVID-19, there is still limited information on renal complications associated with COVID-19 in children. The cause of kidney involvement in COVID-19 is likely multifactorial, and appears to involve a complex process, including complement dysregulation and thrombotic microangiopathy. We present a pediatric case of COVID-19 and renal failure due to thombotic microangiopathy, successfully treated with eculizumab.
All Keywords
【초록키워드】 COVID-19, Hospitalized, pediatric, children, Acute kidney injury, kidney, Complication, information, complex, thrombotic, renal, complement dysregulation, while, multifactorial, treated, appear, with COVID-19, 【제목키워드】 Treatment, pediatric, eculizumab, renal, patient with COVID-19,
【초록키워드】 COVID-19, Hospitalized, pediatric, children, Acute kidney injury, kidney, Complication, information, complex, thrombotic, renal, complement dysregulation, while, multifactorial, treated, appear, with COVID-19, 【제목키워드】 Treatment, pediatric, eculizumab, renal, patient with COVID-19,
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COVID-19로 입원한 성인들 사이에서 급성 신장 손상에 대한 보고가 증가하고 있지만, 어린이의 COVID-19와 관련된 신장 합병증에 대한 정보는 여전히 제한적입니다. COVID-19의 신장 관련 원인은 다인자일 가능성이 있으며 보체 조절 장애 및 혈전성 미세혈관병증을 포함한 복잡한 과정을 포함하는 것으로 보입니다. 우리는 에쿨리주맙으로 성공적으로 치료된 코로나19 및 혈전성 미세혈관병증으로 인한 신부전의 소아 증례를 제시합니다.