Abstract
This review focuses on adaptive immune responses against SARS-CoV-2, the coronavirus that causes COVID-19. A great deal of work has been accomplished in a very short period of time to describe adaptive immune responses and to ascertain their roles in determining the course of infection. As with other viral infections, SARS-CoV-2 elicits both antibody and T-cell responses. Whereas antibody responses are likely effective in preventing infection and may participate in controlling infection once established, it is less clear whether or not they play a role in pathogenesis. T cells are likely involved in controlling established infection, but a pathogenic role is also possible. Longer term evaluation is necessary to determine the durability of protective immune responses.
Keywords: Antibody; Epitopes; Immunity; Neutralization; SARS-CoV-2; T cells.
【저자키워드】 SARS-CoV-2, Immunity, antibody, T cells, neutralization, Epitopes, 【초록키워드】 COVID-19, coronavirus, Pathogenesis, T cells, Antibody Response, Infection, viral infections, T cell, immune responses, Adaptive immune response, T-cell responses, Protective, pathogenic, effective, Course, involved, less, determine, elicit, cause, preventing infection, 【제목키워드】 immune response,