The current pandemic of coronavirus disease (COVID-19) caused by SARS-CoV-2 is a significant global health challenge. A recent study by Carvelli and colleagues now demonstrates the involvement of complement C5a and its receptor C5aR1 in disease progression and suggests that blockade of the C5a-C5aR1 axis may represent a potential therapeutic strategy against COVID-19.
All Keywords
【저자키워드】 COVID-19, SARS-CoV-2, Drug discovery, complement system, GPCRs, cellular signaling,
【저자키워드】 COVID-19, SARS-CoV-2, Drug discovery, complement system, GPCRs, cellular signaling,