Abstract
Background : We aimed to determine the anti-SARS-CoV-2 IgG antibodies among people living with HIV (PLHIV) in Pune, India. Methods : This cross-sectional study was conducted between March 2021 and June 2021. Demographic and clinical information related to coronavirus disease 2019 (COVID-19) were recorded on structured questionnaires. Blood samples were collected and tested for anti-SARS-CoV-2 IgG antibodies using commercial ELISA. Results : Of the 405 HIV infected individuals enrolled in the study, 223(55.1%) were females. Mean age and CD4 count of participants were 42 years (SD: 10) and 626 cells/mm 3 (SD: 284) respectively. A total of 382 (95%) PLHIV were virologically suppressed. The seropositivity against SARS-CoV-2 was found in 221 PLHIV (54.6%, 95% CI: 49.7-59.4). No significant association was found between demographic or clinical factors and seropositivity. Conclusion : A high prevalence of anti-SARS-CoV-2 IgG antibodies was found among PLHIV attending ART centre indicating an exposure to the virus among them.
Keywords: COVID-19; HIV; SARS-CoV-2; antibodies; seroprevalence.
【저자키워드】 COVID-19, antibodies, SARS-CoV-2, HIV, seroprevalence., 【초록키워드】 coronavirus disease, cross-sectional, India, virus, CD4, ELISA, Prevalence, ART, age, demographic, association, Questionnaires, infected individual, blood sample, clinical information, participant, PLHIV, females, Result, enrolled, tested, collected, conducted, determine, suppressed, with HIV, were recorded, anti-SARS-CoV-2 IgG antibody, clinical factor, 【제목키워드】 IgG, Seroprevalence, ART, individual, Attending,