Abstract
Transplantation in potential candidates who have recently recovered from COVID-19 is a challenge with uncertainties regarding the diagnosis, multi-organ systemic involvement, prolonged viral shedding in immunocompromised patients, and optimal immunosuppression. A 42 year male with alcoholic hepatitis underwent a successful deceased donor liver transplantation 71 days after the initial diagnosis of COVID-19. At the time of transplant, he was SARS-CoV-2 PCR negative for 24 days and had a MELD score of 33. His post-operative course was complicated by acute rejection which responded to intense immune-suppression using T-cell depletion and steroids. He was discharged with normal end-organ function and no evidence of any active infection including COVID-19. Prospective organ transplant recipients who have recovered from COVID-19 can be considered for transplantation after careful pre-transplant evaluation, donor selection, and individualized risk-benefit analysis.
Keywords: COVID-19; coronavirus; liver transplantation.
【저자키워드】 COVID-19, coronavirus, Liver transplantation, 【초록키워드】 Infection, Immunocompromised patients, Diagnosis, Immunosuppression, Organ transplant, Steroids, Hepatitis, Prospective, male, Liver transplantation, T-cell, prolonged viral shedding, Donor, Evidence, Deceased, SARS-CoV-2 PCR, transplantation, Risk-benefit analysis, candidate, recipient, rejection, initial, Course, discharged, diagnosis of COVID-19, end-organ, 【제목키워드】 Patient, Liver transplantation,