Abstract
The coronavirus disease 2019 (COVID-19) pandemic has triggered a sudden global change in healthcare systems. Cancer patients have a higher risk of death from COVID-19 in comparison to patients without cancer. Many studies have stated that various factors, such as older age, frequent exposure to healthcare, and higher smoking rates are responsible for the complications of COVID-19. We hypothesize that side effects of chemotherapy, such as cellular senescence, could worsen COVID-19. Given this situation, in this review, we highlight the updated findings of research investigating the impact of cellular senescence on COVID-19 complications and explored potential therapeutic targets for eliminating senescent cells during the COVID-19 pandemic.
Keywords: COVID-19; Cancer; Chemotherapy; Pandemic; Senescence.
【저자키워드】 COVID-19, pandemic, Cancer, senescence, Chemotherapy, 【초록키워드】 coronavirus disease, COVID-19 pandemic, senescence, smoking, healthcare, Research, Patient, Older age, Factors, death, cellular senescence, Healthcare systems, Side effect, higher risk, complications of COVID-19, potential therapeutic target, highlight, responsible, triggered, eliminating, COVID-19 complication, global change, senescent cell, 【제목키워드】 cellular senescence, complications of COVID-19,