Abstract
COVID-19 generates a complex systemic inflammatory response that can lead to death due to wide macrophage activation, endothelial damage, and coagulation in critically ill patients. SARS-CoV-2-induced lung injury due to inflammatory mediated thrombosis could be similar to the livedoid vasculopathy in the skin, supporting a translational comparison of these clinical settings. In this article, we discuss anticoagulation, suppression of inflammatory response, and hyperbaric oxygen therapy in the context of severe COVID-19 and livedoid vasculopathy.
Keywords: COVID-19; heparin; hyperbaric oxygenation; livedoid; thrombosis; vasculopathy.
All Keywords
【저자키워드】 COVID-19, thrombosis, heparin, Hyperbaric oxygenation, Vasculopathy, livedoid, 【초록키워드】 anticoagulation, severe COVID-19, endothelial damage, Lung injury, Coagulation, death, Oxygen therapy, macrophage activation, critically ill patients, Inflammatory response, Inflammatory, complex, systemic inflammatory response, clinical settings, generate, translational, 【제목키워드】 Inflammation, anticoagulation, Oxygen therapy, Reasoning, condition,
【저자키워드】 COVID-19, thrombosis, heparin, Hyperbaric oxygenation, Vasculopathy, livedoid, 【초록키워드】 anticoagulation, severe COVID-19, endothelial damage, Lung injury, Coagulation, death, Oxygen therapy, macrophage activation, critically ill patients, Inflammatory response, Inflammatory, complex, systemic inflammatory response, clinical settings, generate, translational, 【제목키워드】 Inflammation, anticoagulation, Oxygen therapy, Reasoning, condition,
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COVID-19는 중환자에서 광범위한 대식세포 활성화, 내피 손상 및 응고로 인해 사망으로 이어질 수 있는 복잡한 전신 염증 반응을 생성합니다. 염증 매개 혈전증으로 인한 SARS-CoV-2 유도 폐 손상은 피부의 리베도이드 혈관병증과 유사할 수 있어 이러한 임상 환경의 번역 비교를 뒷받침합니다. 이 기사에서는 중증 COVID-19 및 리베노이드 혈관병증의 맥락에서 항응고, 염증 반응 억제, 고압 산소 요법에 대해 논의합니다.
{{ 키워드: }} 코로나19; 헤파린; 고압산소화; 리베도이드; 혈전증; 혈관병증.