Abstract
Increased morbidity and mortality from coronavirus disease 2019 (COVID-19) in people with obesity have illuminated the intersection of obesity with impaired responses to infections. Although data on mechanisms by which COVID-19 impacts health are being rapidly generated, there is a critical need to better understand the pulmonary, vascular, metabolic, and immunologic aspects that drive the increased risk for complications from COVID-19 in people with obesity. This review provides a broad overview of the intersection between COVID-19 and the physiology of obesity in order to highlight potential mechanisms by which COVID-19 disease severity is increased by obesity and identify areas for future investigation toward developing tailored therapy for people with obesity who develop COVID-19.
【초록키워드】 COVID-19, coronavirus disease, therapy, obesity, Health, infections, response, Impact, Complication, morbidity and mortality, Critical, mechanism, Vascular, potential mechanism, increased risk, COVID-19 disease severity, Intersection, highlight, identify, develop, provide, Increased, 【제목키워드】 COVID-19,