Background The aim of the study is to estimate the prevalence of atelectasis assessed with computer tomography (CT) in SARS-CoV-2 pneumonia and the relationship between the amount of atelectasis with oxygenation impairment, Intensive Care Unit admission rate and the length of in-hospital stay. Patients and methods Two-hundred thirty-seven patients admitted to the hospital with SARS-CoV-2 pneumonia diagnosed by clinical, radiology and molecular tests in the nasopharyngeal swab who underwent a chest computed tomography because of a respiratory worsening from Apr 1 to Apr 30, 2020 were included in the study. Patients were divided into three groups depending on the presence and amount of atelectasis at the computed tomography: no atelectasis, small atelectasis (< 5% of the estimated lung volume) or large atelectasis (> 5% of the estimated lung volume). In all patients, clinical severity, oxygen-therapy need, Intensive Care Unit admission rate, the length of in-hospital stay and in-hospital mortality data were collected. Results Thirty patients (19%) showed small atelectasis while eight patients (5%) showed large atelectasis. One hundred and seventeen patients (76%) did not show atelectasis. Patients with large atelectasis compared to patients with small atelectasis had lower SatO 2 /FiO 2 (182 vs 411 respectively, p = 0.01), needed more days of oxygen therapy (20 vs 5 days respectively, p = 0,02), more frequently Intensive Care Unit admission (75% vs 7% respectively, p < 0.01) and a longer period of hospitalization (40 vs 14 days respectively p < 0.01). Conclusion In patients with SARS-CoV-2 pneumonia, atelectasis might appear in up to 24% of patients and the presence of larger amount of atelectasis is associated with worse oxygenation and clinical outcome. Supplementary Information The online version contains supplementary material available at 10.1186/s12890-021-01638-9.
【저자키워드】 coronavirus, mechanical ventilation, Chest computed tomography, Atelectasis, Severe acute respiratory syndrome, 【초록키워드】 Hospitalization, Pneumonia, computer tomography, hospital, intensive care unit, lung, oxygen, Clinical outcome, Prevalence, Computed tomography, Chest computed tomography, Atelectasis, Nasopharyngeal swab, Patient, Oxygen therapy, SARS-CoV-2 pneumonia, respiratory, Admission, patients, in-hospital mortality, Molecular tests, Clinical severity, Oxygenation, In-hospital, Volume, supplementary material, worsening, three groups, oxygen-therapy, oxygenation impairment, molecular test, Result, collected, diagnosed, eight, three group, patients with SARS-CoV-2, 【제목키워드】 SARS-CoV-2, Computed tomography, Atelectasis, retrospective cohort study, clinical consequence,