Abstract
Given the devastating consequences of the current COVID-19 pandemic and its impact on all of us, the question arises as to whether manipulating the cellular degradation (recycling, waste disposal) mechanism known as macroautophagy/autophagy (in particular, the selective degradation of virus particles, termed virophagy) might be a beneficial approach to fight the novel coronavirus, SARS-CoV-2. Knowing that “autophagy can reprocess everything”, it seems almost inevitable that, sooner rather than later, a further hypothesis-driven work will detail the role of virophagy as a fundamental “disposal strategy” against COVID-19, yielding most needed therapeutic interventions. Abbreviations: ATG, autophagy-related; CoV/CoVs coronavirus/coronaviruses; COVID-19, coronavirus disease 2019; MERS-CoV, Middle East respiratory syndrome coronavirus; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2.
Keywords: Autophagy; coronavirus; disposal; virophagy; virus.
【저자키워드】 coronavirus, autophagy, virus., Disposal, virophagy, 【초록키워드】 COVID-19, coronavirus disease, SARS-CoV-2, COVID-19 pandemic, virus, MERS-CoV, Novel coronavirus, Degradation, mechanism, cellular, Middle East, waste disposal, acute respiratory syndrome, syndrome, therapeutic interventions, virus particles, selective, approach, consequence, question, arise, yielding, 【제목키워드】 COVID-19,