Onychomycosis is a fungal infection of nails primarily caused by dermatophyte fungi. Fungi are traditionally understood as existing in the environment as planktonic organisms; however, recent advancements in microbiology suggest that fungi form biofilms-complex sessile microbial communities irreversibly attached to epithelial surfaces by means of an extracellular matrix. The extracellular matrix also acts as a protective barrier to the organisms within the biofilm. The biofilm is surprisingly resistant to injury and may act as a persistent source of infection possibly accounting for antifungal resistance in onychomycosis.
All Keywords
【저자키워드】 biofilm, Antifungal, Extracellular matrix, Nail, Onychomycosis, dermatophyte fungi,
【저자키워드】 biofilm, Antifungal, Extracellular matrix, Nail, Onychomycosis, dermatophyte fungi,