Objective Herd immunity is achieved when in a population, immune individuals are in a sufficiently large proportion. Neutralizing antibodies specific to SARS-CoV-2 that are produced following infection or vaccination are critical for controlling the spread of COVID-19. The objective of the present work was to investigate the rate of SARS-CoV-2 natural immunization in Gabonese. Results One thousand, four hundred and ninety two people were enrolled. The overall prevalence of anti-SARS-CoV-2 antibodies was 36.2%. Moreover, 76.4% of people who developed a humoral response to SARS-CoV-2 produced both anti-SARS-CoV-2 N-protein antibodies and anti-SARS-CoV-2 S-protein antibodies, which correspond to 27.7% of the total population. In infants (0–9 month), children (1–17 years) and adults, the prevalence of anti-SARS-CoV-2 antibodies was relatively the same, between 33 and 37% (any antibody types) and between 25 and 28.6% (neutralizing antibodies). In this African context, one-third (1/3) of the screened population was exposed to SARS-CoV-2 and three-quarter (3/4) of those exposed individuals developed neutralizing antibodies against SARS-CoV-2. This data suggest that herd immunity is not yet to be achieved in Gabon.
【저자키워드】 antibodies, SARS-CoV-2, children, Infants, Adults, 【초록키워드】 neutralizing antibody, vaccination, Immunity, Neutralizing antibodies, antibody, Infection, anti-SARS-CoV-2, immunization, immune, Infant, Prevalence, anti-SARS-CoV-2 antibodies, Infants, Humoral response, anti-SARS-CoV-2 antibody, herd immunity, African, Critical, S-protein, Gabon, humoral, individual, total population, objective, spread of COVID-19, Result, enrolled, produced, proportion, screened, 【제목키워드】 Immunity, antibody, nucleocapsid, African,