Highlights • Most children received the first dose of primary vaccines on time. • Timeliness of vaccination decreased with vaccine dose. • Most children had appropriate intervals between doses; marked variation occurred. • The quality of routine vaccination records in Wales is high. • Parental report of MMR status is reliable. Background To achieve full benefits of vaccination programmes, high uptake and timely receipt of vaccinations are required. Objectives To examine uptake and timeliness of infant and pre-school booster vaccines using cohort study data linked to health records. Methods We included 1782 children, born between 2000 and 2001, participating in the Millennium Cohort Study and resident in Wales, whose parents gave consent for linkage to National Community Child Health Database records at the age seven year contact. We examined age at receipt, timeliness of vaccination (early, on-time, delayed, or never), and intervals between vaccine doses, based on the recommended schedule for children at that time, of the following vaccines: primary (diphtheria, tetanus, pertussis (DTP), polio, Meningococcal C (Men C), Haemophilus influenzae type b (Hib)); first dose of measles, mumps and rubella (MMR); and pre-school childhood vaccinations (DTP, polio, MMR). We compared parental report with child health recorded MMR vaccination status at age three years. Results While 94% of children received the first dose of primary vaccines early or on time, this was lower for subsequent doses (82%, 65% and 88% for second and third doses and pre-school booster respectively). Median intervals between doses exceeded the recommended schedule for all but the first dose with marked variation between children. There was high concordance (97%) between parental reported and child health recorded MMR status. Conclusions Routine immunisation records provide useful information on timely receipt of vaccines and can be used to assess the quality of childhood vaccination programmes. Parental report of MMR vaccine status is reliable.
【저자키워드】 vaccination, Timeliness, Child, Millennium Cohort Study (MCS), Child health systems,