Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma

혈장 내 항파상풍 항체 평가를 위한 재조합 단편 C의 유용성

Published on
Journal: Diagnostic Microbiology and Infectious Disease
[저자] Girija Ramakrishnan, Karl Pedersen, Denis Guenette, Joyce Sink, Rashidul Haque, William A. Petri, Joel Herbein, Carol A. Gilchrist
[Category] 파상풍,
Pubmed URL    DOI URL    [DOI] 10.1016/j.diagmicrobio.2015.01.016    
[Article Type] journal-article
[Source] pubmed

Anti-tetanus antibodies in biological samples are typically detected using an enzyme-linked immunosorbent assay based on toxoided tetanus neurotoxin as antigen. We demonstrate that recombinantly produced fragment C of the toxin heavy chain is an effective alternative antigen for assessment of tetanus-immune status in plasma samples.

All Keywords
【저자키워드】 immune response, ELISA, Tetanus, recombinant antigen, Fragment C, Vaccine surveillance.,