Introduction Chest X-ray (CXR) is used for the initial triage of patients with suspected COVID-19. Studies of CXR scoring in the European population found a higher score in males than in females and significantly correlated with age. Because there have not been studies in the Mexican-mestizo community, we aimed to compare the differences in CXR scores between males and females and their correlation with age after controlling comorbidities like diabetes and hypertension. Materials and Methods A retrospective study of 1000 CXR of Mexican-mestizo patients with SARS-CoV-2 infection, confirmed by RT-PCR. Significant differences between age, age groups, symptoms, comorbidities, and CXR scores between males and females used the Mann–Whitney U , Chi-square tests ( χ 2 ), and Kruskal–Wallis tests. The relationship between the total CXR score and age was measured with the Spearman rank correlation coefficient (Rs); partial correlation analysis controlled the effect of symptoms, risk factors, and comorbidities. Results The total CXR score did not show a difference between males and females grouped by age. There was a positive, low correlation between the total CXR score and age in males, Rs = 0.260, p < 0.001 ( N = 616), and in females, Rs = 0.170, p = 0.001 ( N = 384). Age only explained a <9% variance of CXR severity. Rs decreased its magnitude (from Rs = 0.152 to Rs = 0.046) and lost its significance (change in p value from p < 0.001 to p = 0.145) after controlling the effect of hypertension. Conclusions There is no significant difference in CXR score between males and females in the Mexican-mestizo population grouped by age. Hypertension cancels the significance of CXR severity with age pointing to its role in the pathophysiology of COVID-19. Further research using stratified groups by age and gender in other populations needs to be published.
【초록키워드】 COVID-19, Risk factors, severity, Infection, Comorbidities, Comorbidity, RT-PCR, hypertension, Symptoms, Population, X-ray, Retrospective study, pathophysiology, male, female, Research, Patient, Community, age, correlation, group, Analysis, CXR, no significant difference, European population, material, positive, Chi-square, Spearman rank correlation, females, males, initial, Result, was measured, significantly, explained, correlated, magnitude, groups, Significant, diabete, stratified, age and gender, Kruskal–Wallis, partial correlation, patients with SARS-CoV-2, 【제목키워드】 COVID-19,