Many studies have investigated post-COVID symptoms, but the predictors of symptom persistence remain unknown. The objective was to describe the natural course of the disease at 6 months and to identify possible factors favoring the resurgence or persistence of these symptoms. COVEVOL is a retrospective observational descriptive study of 74 patients. All patients with positive SARS-CoV-2 PCR from March 2020 were included. We compared a group with symptom persistence (PS group) with another group without symptom persistence (no-PS group). Fifty-three out of seventy-four patients (71.62%) described at least one persistent symptom at 6 months of SARS-CoV-2 infection. In the PS group, 56.6% were women and the average age was 54.7 years old [21–89.2] ± 16.9. The main symptoms were asthenia (56.6%, n = 30), dyspnea (34%, n = 18), anxiety (32.1% n = 17), anosmia (24.5%, n = 13) and agueusia (15.1% n = 8). Ten patients (13.51%) presented a resurgence in symptoms. Patients in the PS group were older ( p = 0.0048), had a higher BMI ( p = 0.0071), and were more frequently hospitalized ( p = 0.0359) compared to the no-PS group. Odynophagia and nasal obstruction were less present in the inaugural symptoms of COVID-19 in the PS group ( p = 0.0202 and p = 0.0332). Persistent post-COVID syndromes are common and identification of contributing factors is necessary for understanding this phenomenon and appropriate management.
【저자키워드】 Risk factors, Anxiety, Anosmia, Dyspnea, post-COVID-19, persistent symptoms, “long COVID”, asthenia, 【초록키워드】 Hospitalized, SARS-COV-2 infection, nasal, Symptom, Symptoms, persistence, management, Patient, age, women, predictor, persistent, BMI, patients, retrospective, odynophagia, Older, Factor, average, syndrome, these symptoms, symptoms of COVID-19, positive SARS-CoV-2 PCR, Course, described, identify, investigated, the disease, less, 【제목키워드】 COVID-19, natural, Month,