Background Due to the wide spread of SARS-CoV2 around the world, the risk of death in individuals with metabolic comorbidities has dangerously increased. Mexico has a high number of infected individuals and deaths by COVID-19 as well as an important burden of metabolic diseases; nevertheless, reports about features of Mexican individuals with COVID-19 are scarce. The aim of this study was to evaluate demographic features, clinical characteristics and the pharmacological treatment of individuals who died by COVID-19 in the south of Mexico. Methods We performed an observational study including the information of 185 deceased individuals with confirmed diagnoses of COVID-19. Data were retrieved from medical records. Categorical data were expressed as proportions (%) and numerical data were expressed as mean ± standard deviation. Comorbidities and overlapping symptoms were plotted as Venn diagrams. Drug clusters were plotted as dendrograms. Results The mean age was 59.53 years. There was a male predominance (60.1%). The mean hospital stay was 4.75 ± 4.43 days. The most frequent symptoms were dyspnea (88.77%), fever (71.42%) and dry cough (64.28%). Present comorbidities included diabetes (60.63%), hypertension (59.57%) and obesity (43.61%). The main drugs used for treating COVID-19 were azithromycin (60.6%), hydroxychloroquine (53.0%) and oseltamivir (27.3%). Conclusions Mexican individuals who died of COVID-19 had shorter hospital stays, higher frequency of shortness of breath, and higher prevalence of diabetes than individuals from other countries. Also, there was a high frequency of off-label use of drugs for their treatment.
【초록키워드】 COVID-19, Treatment, oseltamivir, SARS-CoV2, Hydroxychloroquine, Clinical characteristics, obesity, hospital, Comorbidity, Symptom, drug, hypertension, Spread, Prevalence, Features, Fever, Dyspnea, male, death, Cluster, age, information, diagnose, Frequency, Deceased, pharmacological treatment, medical records, Shortness of breath, risk of death, overlapping, Standard deviation, individual, dry cough, present, treating COVID-19, off-label, mean hospital stay, feature, Result, performed, evaluate, died, proportion, were expressed, number of infected, diabete, individuals with COVID-19, retrieved, Venn diagrams, 【제목키워드】 COVID-19, hospital, Patient, Observational cohort study, died,