Shigella sonnei UCN59, isolated during an outbreak of S. sonnei in January 2007, was resistant to azithromycin (MIC 64 mg/L). The isolate contained a plasmid-borne mph (A) gene encoding a macrolide 2′-phosphotransferase that inactivates macrolides. Emergence of the mph (A) gene in S. sonnei may limit usefulness of azithromycin for treatment of shigellosis.
All Keywords
【저자키워드】 Azithromycin, Surveillance, outbreak, Antibiotic resistance, dispatch, Shigellosis,
【저자키워드】 Azithromycin, Surveillance, outbreak, Antibiotic resistance, dispatch, Shigellosis,