SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Here, we investigated the interaction of this new coronavirus with Vero cells using high resolution scanning electron microscopy. Surface morphology, the interior of infected cells and the distribution of viral particles in both environments were observed 2 and 48 h after infection. We showed areas of viral processing, details of vacuole contents, and viral interactions with the cell surface. Intercellular connections were also approached, and viral particles were adhered to these extensions suggesting direct cell-to-cell transmission of SARS-CoV-2.
All Keywords
【저자키워드】 SARS-CoV-2, Virology, 【초록키워드】 COVID-19 pandemic, Infection, Microscopy, morphology, surface, distribution, Interaction, connection, extension, infected cell, viral particle, transmission of SARS-CoV-2, Vero Cell, Cell, this new coronavirus, interior, investigated, 【제목키워드】 Microscopy, Interaction, Analysis, host cell,
【저자키워드】 SARS-CoV-2, Virology, 【초록키워드】 COVID-19 pandemic, Infection, Microscopy, morphology, surface, distribution, Interaction, connection, extension, infected cell, viral particle, transmission of SARS-CoV-2, Vero Cell, Cell, this new coronavirus, interior, investigated, 【제목키워드】 Microscopy, Interaction, Analysis, host cell,