We report pertussis cases in 4 infants less than 6 months admitted with symptoms compatible with pertussis to the intensive care unit of the Università Cattolica del Sacro Cuore in Rome, April 2014. Realtime PCR confirmed pertussis diagnosis for the 4 infants, 2 of them were cousins, and for the household contacts of 1 of them. Analysis of pertussis toxin, its promoter and pertactin was also performed. First of all, this report emphasizes the need to investigate household contact of infants with pertussis; secondly, to evaluate the selective vaccination of household members of newborns as an effective program to reduce pertussis in infants.
All Keywords
【저자키워드】 Vaccine, Italy, Infant, household contacts, pertussis, prn, pertactin, ptxA, subunit S1 of the pertussis toxin, ptxP, promoter of the pertussis toxin gene,
【저자키워드】 Vaccine, Italy, Infant, household contacts, pertussis, prn, pertactin, ptxA, subunit S1 of the pertussis toxin, ptxP, promoter of the pertussis toxin gene,