Bordetella pertussis causes whooping cough and is re-emerging in developed countries despite widespread immunization with acellular pertussis vaccines (Pa), which are less effective than the whole cell vaccines that they replaced. Efficacy of Pa could be improved by switching from alum to alternative adjuvants that generate more potent cell mediated immunity.
All Keywords
【저자키워드】 Vaccine, adjuvant, Cell mediated immunity, Bordetella pertussis, Th1 cell, Whooping cough,
【저자키워드】 Vaccine, adjuvant, Cell mediated immunity, Bordetella pertussis, Th1 cell, Whooping cough,