[[[ Introduction: ]]] We investigated whether muscle ultrasound can distinguish muscles affected by post-polio syndrome (PPS) from healthy muscles and whether severity of ultrasound abnormalities is associated with muscle strength. [[[ Methods: ]]] Echo intensity, muscle thickness, and isometric strength of the quadriceps muscles were measured in 48 patients with PPS and 12 healthy controls. [[[ Results: ]]] Patients with PPS had significantly higher echo intensity and lower muscle thickness than healthy controls. In patients, both echo intensity and muscle thickness were associated independently with muscle strength. A combined measure of echo intensity and muscle thickness was more strongly related to muscle strength than either parameter alone. [[[ Conclusions: ]]] Quantitative ultrasound distinguishes healthy muscles from those affected by PPS, and measures of muscle quality and quantity are associated with muscle strength. Hence, ultrasound could be a useful tool for assessing disease severity and monitoring changes resulting from disease progression or clinical intervention in patients with PPS.
Quantitative muscle ultrasound and quadriceps strength in patients with post‐polio syndrome
양적 근육 초음파 및 폴리오 후 증후군 환자의 대퇴사두근 힘
[Category] 폴리오,
[Article Type] journal-article
[Source] pubmed
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