Background Possible cases of SARS-CoV-2 infection were diagnosed in primary care in Madrid, some of these cases had pneumonia. Most of the SARS-CoV-2 pneumonia published data came from hospitalised patients. This study set out to describe clinical characteristics of patients with SARS-CoV-2 pneumonia diagnosed in primary care across age groups and type of pneumonia. Methods Observational retrospective study obtaining clinical data from the electronic health records of patients who were followed-up by SARS-CoV-2 possible infection in a primary care practice in Madrid. All the cases were collected by in-person or remote consultation during the 10th March to the 7th of April. Exposure: Diagnosis of SARS-CoV-2 pneumonia by chest X-ray ordered by the GP. Main outcomes and measures: Symptoms of SARS-CoV-2 pneumonia, physical examination and diagnostic tests as a blood test, nasopharyngeal swab results for RT-PCR (Reverse transcriptase-polymerase chain reaction) and chest X-ray results. Results The overall SARS-CoV-2 pneumonias collected were 172 (female 87 [50.6%], mean age 60.5 years standard deviation [SD] 17.0). Comorbidities were body mass index ≥ 25 kg/m 2 (90 [52.3%]), hypertension (83 [48.3%]), dyslipidaemia (68 [39.5%]) and diabetes (33 [19.2%]). The sample was stratified by age groups (< 50 years, 50–75 years and ≥ 75 years). Clinical manifestations at onset were fever (144 [83.7%]), cough (140 [81.4%]), dyspnoea (103 [59.9%]) and gastrointestinal disturbances (72 [41.9%]). Day 7.8 (SD:4.1) from clinical onset was the mean day of pneumonia diagnosis. Bilateral pneumonia was more prevalent than unilateral (126 [73.3%] and 46 [26.7%]). Patients with unilateral pneumonia were prone to higher pulse oximetry (96% vs 94%, p < 0.001). We found differences between unilateral and bilateral cases in C-reactive protein (29.6 vs 81.5 mg/L, p < 0.001), and lymphocytes (1400.0 vs 1000.0E3/ml, p < 0.001). Complications were registered: 42 (100%) of patients ≥ 75 years were admitted into hospital; pulmonary embolism was only present at bilateral pneumonia (7 patients [5.6%]) and death occurred in 1 patient with unilateral pneumonia (2.2%) vs 10 patients (7.9%) with bilateral pneumonia ( p 0.170). Conclusion Clinical manifestations of SARS-CoV-2 pneumonia were fever, cough and dyspnoea; this was especially clear in the elderly. We described different characteristics between unilateral and bilateral pneumonia. Supplementary Information The online version contains supplementary material available at 10.1186/s12875-021-01430-y.
【저자키워드】 COVID-19, SARS-CoV-2, primary care, Pneumonia, 【초록키워드】 primary care, Lymphocytes, Clinical characteristics, Pneumonia, pulse oximetry, SARS-COV-2 infection, diagnostic test, Infection, Comorbidities, Diagnosis, C-reactive protein, diabetes, outcome, cough, RT-PCR, hypertension, Electronic health record, clinical manifestations, Retrospective study, Nasopharyngeal swab, lymphocyte, body mass index, Physical examination, Characteristics, diagnostic tests, Pulmonary embolism, Fever, female, Patient, death, Complication, age, Hospitalised patients, chest X-ray, SARS-CoV-2 pneumonia, group, Blood, blood test, Dyspnoea, Gastrointestinal disturbances, Electronic health records, reverse transcriptase-polymerase chain reaction, reverse transcriptase, Chain Reaction, clinical manifestation, body mass, pneumonias, Standard deviation, supplementary material, Clinical data, bilateral pneumonia, dyslipidaemia, MOST, prevalent, Result, described, collected, occurred, diagnosed, Day, the mean, diabete, stratified, Bilateral, patients with SARS-CoV-2, the SARS-CoV-2, 【제목키워드】 Pneumonia, Characteristics, clinical, Spain, diagnosed,