We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.
All Keywords
【저자키워드】 antimicrobial resistance, ciprofloxacin, Bacteria, Salmonella, treatment failure, typhoid fever, dispatch, expedited, gyrB,
【저자키워드】 antimicrobial resistance, ciprofloxacin, Bacteria, Salmonella, treatment failure, typhoid fever, dispatch, expedited, gyrB,