Background and Objectives: This observational prospective study aims to examine the psychological and psychopathological impact of the pandemic stress on patients with pre-existing mood, anxiety and obsessive–compulsive disorders. Materials and Methods: The study includes 386 consecutive patients recruited from 10 March to 30 June 2020 among those being treated at the Institute of Psychopathology in Rome (Italy) with an age ≥18 years and meeting DSM-5 criteria for major depressive disorder (MDD) (35.2%), bipolar I (BD-I) (21.5%) or II (BD-II) (28.8%) disorder, obsessive–compulsive disorder (OCD) (7.5%), panic disorder (PD) (7.0%) or social anxiety (SA). A total of 34.2% had lifetime comorbid Axis I disorders and 15.3% had alcohol/drug abuse disorders. Using a semi-structured interview, we investigated if the impact of COVID-19 stress for patients has been similar, higher or lower than that of their family and friends and, for patients with relapse/symptoms worsening, if there was a relationship between the clinical condition worsening and the pandemic stress. Results: Compared with that experienced by their family members and friends, the psychological impact of pandemic stress was similar in 52.1% of the sample, better in 37.1% and worse in 10.8%. In 21 patients (5.4%), the stress triggered a recurrence or worsened the symptoms. Patients with OCD had a higher rate of worsening due to pandemic stress compared to patients with MDD ( p = 0.033), although, overall, the χ 2 test was not significant among primary diagnoses (χ 2 = 8.368; p = 0.057). Conclusions: The psychological and psychopathological consequences of COVID-19 stress in our outpatients were very modest. The continuity of care offered during the lockdown could explain the results.
【저자키워드】 coronavirus, psychological Impact, Bipolar disorder, Panic disorder, major depressive disorder, social anxiety disorder, obsessive–compulsive disorder, 【초록키워드】 COVID-19, pandemic, Anxiety, Stress, lockdown, OCD, Prospective Study, Italy, Symptoms, Patient, Psychopathology, age, Psychological, Care, diagnose, Outpatient, criteria, not significant, disorders, worsening, depressive, material, clinical condition, disorder, Rome, axis, DSM-5, consequence, include, recruited, investigated, treated, triggered, explain, consecutive patient, offered, their family member, worsened, 【제목키워드】 COVID-19, Impact, Prospective, mood,