Background Coronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission. Methods A total of 71 age-matched pediatric IA and COVID-19 patient pairs were formed and their clinical data on admission were compared. Results Fever, cough, nasal congestion and nausea/vomiting were the most common symptoms on admission for both infections but occurred less often in COVID-19. The IA patients were more likely to have lower-than-normal levels of lymphocyte count and percentage and to have higher-than-normal levels of activated partial thromboplastin time, prothrombin time, serum C-reactive protein, and serum procalcitonin, while the COVID-19 patients had higher odds of having lower-than-normal levels of neutrophil count and percentage. Conclusions This study suggests that influenza A is more symptomatic than COVID-19 for children and might be an overall more severe infection at the time of admission. Supplementary Information The online version contains supplementary material available at 10.1186/s12879-021-06037-3.
【저자키워드】 Coronavirus disease 2019, influenza A, Retrospective study, pediatrics, 【초록키워드】 COVID-19, coronavirus disease, Coronavirus disease 2019, Severe infection, Clinical characteristics, Influenza, pediatric, children, neutrophil, Infection, C-reactive protein, procalcitonin, Symptom, cough, nasal congestion, influenza A, Lymphocyte count, lymphocyte, serum, symptomatic, Patient, Admission, prothrombin, COVID-19 patients, COVID-19 patient, Prothrombin time, on admission, partial thromboplastin time, activated partial thromboplastin time, serum C-reactive protein, supplementary material, Clinical data, higher odds, neutrophil count, nausea, THROMBOPLASTIN, vomiting, nausea/vomiting, Result, activated, higher odd, occurred less, 【제목키워드】 Coronavirus disease 2019, influenza A, China, Admission, clinical feature,