[[[ Background and objectives: ]]] The aim of this study was to analyse the increase of antitetanus titre in volunteers following injection with human tetanus immunoglobulin (HTI). [[[ Materials and methods: ]]] Twelve females with tetanus antibody titres of < or = 0.05 international units (IU)/ml were injected with 500 IU of human tetanus immunoglobulin (Tetabulin S/D). The tetanus antibody titres were determined before injection, and after 30 h, 48 h and 4 days. [[[ Results: ]]] A fast and sustained increase of protective tetanus antibody levels was observed in 10 of 12 volunteers. No adverse events related to the study drug were reported. [[[ Conclusions: ]]] HTI confers rapid and effective immunity to tetanus.
Tetanus antibody levels of female volunteers after injection with solvent/detergent‐treated human tetanus immunoglobulin (Tetabulin S/D)
용매/세제 처리된 인간 파상풍 면역글로불린(Tetabulin S/D) 주사 후 여성 자원봉사자의 파상풍 항체 수준
[Category] 파상풍,
[Article Type] journal-article
[Source] pubmed
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