Background The global pandemic caused by SARS-CoV-2 has impacted population health and care delivery worldwide. As information emerges regarding the impact of “lockdown measures” and changes to clinical practice worldwide; there is no comparative information emerging from the United Kingdom with regard to major trauma. Methods This observational study from a UK Major Trauma Centre matched a cohort of patients admitted during a 10-week period of the SARS-CoV-2-pandemic (09/03/2020–18/05/2020) to a historical cohort of patients admitted during a similar time period in 2019 (11/03/2019–20/05/2019). Differences in demographics, Clinical Frailty Scale, SARS-CoV-2 status, mechanism of injury and injury severity were compared using Fisher’s exact and Chi-squared tests. Univariable and multivariable logistic regression analyses examined the associated factors that predicted 30-days mortality. Results A total of 642 patients were included, with 405 in the 2019 and 237 in the 2020 cohorts, respectively. 4/237(1.69%) of patients in the 2020 cohort tested positive for SARS-CoV-2. There was a 41.5% decrease in the number of trauma admissions in 2020. This cohort was older (median 46 vs 40 years), had more comorbidities and were frail ( p < 0.0015). There was a significant difference in mechanism of injury with a decrease in vehicle related trauma, but an increase in falls. There was a twofold increased risk of mortality in the 2020 cohort which in adjusted multivariable models, was explained by injury severity and frailty. A positive SARS-CoV-2 status was not significantly associated with increased mortality when adjusted for other variables. Conclusion Patients admitted during the COVID-19 pandemic were older, frailer, more co-morbid and had an associated increased risk of mortality.
【저자키워드】 COVID-19, Mortality, major trauma, Injury severity, ICON-TRAUMA, 【초록키워드】 SARS-CoV-2, COVID-19 pandemic, severity, frailty, Comorbidity, global pandemic, Cohort, Health, clinical, Patient, scale, information, United Kingdom, change, Admission, Care, mechanism, trauma, Clinical practice, Analysis, Injury, demographics, Major, Older, Factor, significant difference, increased risk, multivariable logistic regression, Multivariable models, cohorts, increased mortality, positive, Chi-squared tests, decrease, difference, other variables, Result, tested, predicted, examined, caused, significantly, median, adjusted, explained, increase in, impacted, cohort of patient, had more, 【제목키워드】 lockdown, trauma,