Abstract
Objective: To describe clinical features, diagnostic findings, treatments, and outcomes in patients with new-onset postural orthostatic tachycardia syndrome (POTS) and other autonomic disorders following SARS-CoV-2 infection (COVID-19).
Methods: We retrospectively reviewed medical records for patients who presented with persistent neurologic and cardiovascular complaints between April and December 2020 following COVID-19 infection.
Results: Twenty patients (70% female) were included in this study.Fifteen had POTS, 3 had neurocardiogenic syncope, and 2 had orthostatic hypotension. Six patients had abnormalities on cardiac or pulmonary testing, and 4 had elevated autoimmune or inflammatory markers. All patients were treated with non-pharmacologic therapies, and most required pharmacologic therapies. Six to 8 months after COVID-19, 17 (85%) patients had residual autonomic symptoms, with 12 (60%) unable to return to work.
Conclusions: POTS can follow COVID-19 in previously healthy patients. Appropriate diagnostic investigations and therapies are necessary to identify and treat autonomic dysfunction after COVID-19.
Keywords: COVID-19; Neurocardiogenic syncope; Neurologic complications; Orthostatic hypotension; Postural orthostatic tachycardia syndrome.
【저자키워드】 COVID-19, Neurologic complications, Neurocardiogenic syncope, Orthostatic hypotension, Postural orthostatic tachycardia syndrome., 【초록키워드】 therapy, SARS-COV-2 infection, diagnostic, inflammatory markers, outcome, Symptoms, Clinical features, COVID-19 infection, female, Patient, Autoimmune, patients, Therapies, medical record, dysfunction, Syncope, Tachycardia, syndrome, treat, disorder, abnormality, neurologic, identify, healthy, required, elevated, treated, Appropriate, autonomic, diagnostic investigation, orthostatic, 【제목키워드】 Patient, Tachycardia, syndrome, disorder, case sery, autonomic, orthostatic,