Abstract
Background: Norwegian hospitals have operated within capacity during the COVID-19 pandemic. We present patient and management characteristics, and outcomes for the entire cohort of adult (>18 years) COVID-19 patients admitted to Norwegian intensive care units (ICU) from 10 March to 19 June 2020.
Methods: Data were collected from The Norwegian intensive care and pandemic registry (NIPaR). Demographics, co-morbidities, management characteristics and outcomes are described. ICU length of stay (LOS) was analysed with linear regression, and associations between risk factors and mortality were quantified using Cox regression.
Results: In total, 217 patients were included. The male to female ratio was 3:1 and the median age was 63 years. A majority (70%) had one or more co-morbidities, most frequently cardiovascular disease (39%), chronic lung disease (22%), diabetes mellitus (20%), and obesity (17%). Most patients were admitted for acute hypoxaemic respiratory failure (AHRF) (91%) and invasive mechanical ventilation (MV) was used in 86%, prone ventilation in 38% and 25% of patients received a tracheostomy. Vasoactive drugs were used in 79% and renal replacement therapy in 15%. Median ICU LOS and time of MV was 14.0 and 12.0 days. At end of follow-up 45 patients (21%) were dead. Age, co-morbidities and severity of illness at admission were predictive of death. Severity of AHRF and male gender were associated with LOS.
Conclusions: In this national cohort of COVID-19 patients, mortality was low and attributable to known risk factors. Importantly, prolonged length-of-stay must be taken into account when planning for resource allocation for any next surge.
Keywords: ARDS; ICU; Norway; SARS-CoV2; covid-19; mechanical ventilation; national cohort.
【저자키워드】 COVID-19, ARDS, SARS-CoV2, mechanical ventilation, ICU, Norway, national cohort., 【초록키워드】 pandemic, Risk factors, Mortality, intensive care, COVID-19 pandemic, obesity, severity, hospital, Diabetes Mellitus, intensive care unit, Lung disease, Gender, cardiovascular disease, outcome, risk factor, Cohort, Characteristics, management, male, female, Patient, death, co-morbidity, Linear regression, age, Follow-up, resource, Admission, co-morbidities, COVID-19 patients, association, renal replacement therapy, Invasive mechanical ventilation, Cox regression, COVID-19 patient, Predictive, LOS, AHRF, Prone ventilation, entire cohort, National, hypoxaemic respiratory failure, dead, described, was used, collected, Most patient, analysed, were used, majority, quantified, the median, vasoactive drug, 【제목키워드】 prospective observational study, survival, Coronavirus disease-19, management, ICU patient,