The Impact of COVID-19 Vaccination on the Social Participation of Immunocompromised Persons – Results of a Multicenter Observational Study

Published on
Journal: Frontiers in Public Health
[저자] Gloria Heesen, Dominik Schröder, Frank Müller, Eva Hummers, Frank Klawonn, Marie Mikuteit, Jacqueline Niewolik, Sandra Steffens, Anne Cossmann, Georg Behrens, Alexandra Dopfer-Jablonka, Stephanie Heinemann
[Category] COVID19(2023년), SARS, 임상,
PMC URL    [DOI] 10.3389/fpubh.2022.877623    
[Article Type] Observational Study
[Source] PMC

Abstract
Immunocompromised persons are at an increased risk for a severe SARS-CoV-2 infection and their safety behaviors may influence their social participation. Vaccinated persons have a lower incidence of infection and severe disease when infected compared to non-vaccinated persons. Therefore, their behavior may change and their social participation may increase after a complete vaccination. The aim of this study was to explore social participation of immunocompromised persons before and after complete COVID-19 vaccination. Between March and September 2021, 274 immunocompromised participants were recruited. Survey data were collected at baseline and follow-up from 194 participants including the Index for the Assessment of Health Impairments [IMET], Patient Health Questionnaire-4 [PHQ-4], subjective health status and quality of life. At baseline, participants were not yet completely vaccinated. Complete vaccination was achieved prior to the follow-up questionnaire. IMET scores decreased significantly at follow-up, indicating a higher social participation after complete vaccination. PHQ-4, subjective health status and quality of life did not differ between baseline and follow-up. There were no significant differences across sociodemographic factors. Significant PHQ-4 differences were observed regarding the population size of the participants’ home community. Social participation of immunocompromised persons in our study increased after COVID-19 vaccination. Therefore, social participation should be explored further, especially with regards to the impact of vaccination on groups with a high health risk.
Keywords: COVID-19 vaccination; immunocompromised; observational study; pandemic (COVID-19); social participation.

All Keywords
【저자키워드】 pandemic (COVID-19), observational study, COVID-19 vaccination, Immunocompromised, Social participation, 【초록키워드】 COVID-19, vaccination, pandemic, survey, Infection, risk, Health, Community, Quality of life, Health status, Follow-up, incidence, assessment, group, questionnaire, severe disease, index, no significant difference, increased risk, participant, sociodemographic factors, Complete, severe SARS-CoV-2, not differ, collected, significantly, recruited, Significant, baseline, 【제목키워드】 COVID-19, Participation, Impact, Result, Person,