Abstract
The purpose of this research was to identify risk factors that were independently related to the maintenance of a swallowing dysfunction in patients affected by critical COVID-19. We conducted a prospective observational cohort study of critical patients with COVID-19, who were admitted to a COVID-19 dedicated intensive care unit (ICU) and required prolonged orotracheal intubation (≥48 hours). Demographic and clinical data were collected at ICU admission and/or at hospital discharge or in-hospital death. Swallowing data was based on The Functional Oral Intake Scale (FOIS) and was collected at two distinct moments: initial swallowing assessment and at patient outcome. Patients were divided into two groups according to their FOIS level assigned on the last swallowing assessment: in-hospital resolved dysphagia-patients with FOIS levels 6 and 7; non-resolved dysphagia at hospital outcome-patients with FOIS levels 1 to 5. Nine hundred and twenty patients were included in our study. Results of the multivariate logistic regression model for the prediction of non-resolved dysphagia at hospital outcome in critical COVID-19 patients. indicated that increasing age (p = 0.002), severity at admission (p = 0.015), body mass index (p = 0.008), use of neuromuscular blockers (p = 0.028), presence of neurologic diseases (p = 0.038), presence of Diabetes Mellitus (p = 0.043) and lower FOIS levels on the initial swallowing assessment (p<0.001) were associated with higher chances of presenting dysphagia at hospital outcome. Critical patients with COVID-19 may experience post-acute COVID-19 dysphagia, indicating the need to prepare for the care/rehabilitation of these patients.
【초록키워드】 COVID-19, intensive care, severity, hospital, intubation, outcome, risk factor, ICU, body mass index, Research, Patient, ICU admission, Dysphagia, oral, scale, demographic, disease, Admission, Critical, patients, In-hospital death, In-hospital, dysfunction, swallowing, Clinical data, multivariate logistic regression, hospital discharge, increasing age, blocker, intake, critical COVID-19 patients, neurologic, critical patient, initial, Result, identify, affected, collected, indicated, required, conducted, was collected, assigned, two group, presenting, resolved, FOIS, patients with COVID-19, prospective observational cohort, with COVID-19, 【제목키워드】 COVID-19, Dysphagia, ICU patient,