Abstract
Purpose: Since the SARS-CoV-2 pandemic, countries are overwhelmed by critically ill Coronavirus disease 2019 (COVID-19) patients. As ICU capacity becomes limited we characterized critically ill COVID-19 patients in the Netherlands.
Methods: In this case series, COVID-19 patients admitted to the ICU of the Jeroen Bosch Hospital were included from March 9 to April 7, 2020. COVID-19 was confirmed by a positive result by a RT-PCR of a specimen collected by nasopharyngeal swab. Clinical data were extracted from medical records.
Results: The mean age of the 50 consecutively included critically ill COVID-19 patients was 65 ± 10 years, the mean BMI was 29 ± 4.7 and 66% were men. Seventy-eight percent of patients had ≥1 comorbidity, 34% had hypertension. Ninety-six percent of patients required mechanical ventilation and 80% were ventilated in prone position. Venous thromboembolism was recognized in 36% of patients. Seventy-four percent of patients survived and were successfully discharged from the ICU, the remaining 26% died (median follow up 86 days). The length of invasive ventilation in survivors was 15 days (IQR 12-31).
Conclusions: The survival rate of COVID-19 critically ill patients in our population is considerably better than previously reported. Thrombotic complications are commonly found and merit clinical attention.
Trial registration number: NL2020.07.04.01.
Keywords: COVID-19; Critical care.; Mortality.; SARS- Cov-2.; Venous Thromboembolism..
【저자키워드】 COVID-19, Critical care, Mortality, Venous Thromboembolism, SARS- CoV-2, 【초록키워드】 Prone position, Coronavirus disease 2019, pandemic, mechanical ventilation, Comorbidity, RT-PCR, hypertension, invasive ventilation, ICU, Nasopharyngeal swab, Case series, Critically ill, clinical, Patient, Thromboembolism, Complication, age, survival rate, BMI, patients, COVID-19 patient, Netherlands, medical records, Critically ill patient, Ventilated, positive result, specimen, survivor, men, country, collected, died, reported, required, median, characterized, discharged, survived, the mean, IQR, Jeroen, the SARS-CoV-2, 【제목키워드】 outcome, Characteristics, Critically ill patient, North,