Abstract
Objective: The COVID-19 pandemic is still raging worldwide. While there is significant published evidence on the attributes of patients with COVID-19 from lower-income and middle-income countries, there is a dearth of original research published from Bangladesh, a low-income country in Southeast Asia. Based on a case series from a tertiary healthcare centre, this observational study has explored the epidemiology, clinical profile of patients with COVID-19 and short-term outcomes in Dhaka, Bangladesh.
Design and setting: A total of 422 COVID-19-confirmed patients (via reverse transcription-PCR test) were enrolled in this study (male=271, female=150, 1 unreported). We have compiled medical records of the patients and descriptively reported their demographic, socioeconomic and clinical features, treatment history, health outcomes, and postdischarge complications.
Result: Patients were predominantly male (64%), between 35 and 49 years (28%), with at least one comorbidity (52%), and had COVID-19 symptoms for 1 week before hospitalisation (66%). A significantly higher proportion (p<0.05) of male patients had diabetes, hypertension and ischaemic heart disease, while female patients had asthma (p<0.05). The most common symptoms were fever (80%), cough (60%), dyspnoea (41%) and sore throat (21%). The majority of the patients received antibiotics (77%) and anticoagulant therapy (56%) and stayed in the hospital for an average of 12 days. Over 90% of patients were successfully weaned, while 3% died from COVID-19, and 41% reported complications after discharge.
Conclusion: The diversity of clinical and epidemiological characteristics and health outcomes of patients with COVID-19 across age groups and gender is noteworthy. Our result will inform the clinicians and epidemiologists of Bangladesh of their COVID-19 mitigation effort.
Keywords: COVID-19; epidemiology; infectious diseases; pathology; public health; therapeutics.
【저자키워드】 COVID-19, public health, pathology, Infectious diseases, Epidemiology, Therapeutics, 【초록키워드】 Asthma, COVID-19 pandemic, hospital, Comorbidity, Gender, Antibiotics, Symptom, diabetes, outcome, cough, hypertension, reverse transcription-PCR, discharge, Clinical features, Asia, outcomes, Health, Characteristics, healthcare, Fever, male, Research, Patient, Complication, complications, age, epidemiological, Ischaemic heart disease, group, hospitalisation, Dyspnoea, Evidence, COVID-19 symptom, anticoagulant therapy, medical record, sore throat, clinician, average, effort, COVID-19 mitigation, epidemiologist, while, attribute, over, country, treatment history, enrolled, died, proportion, reported, the patient, case sery, majority, significantly higher, female patient, patients with COVID-19, 【제목키워드】 cross-sectional, hospital, outcome, RT-PCR, clinical, Care, positive patient,